Biologische Verfahrenstechnik

Lehrinhalte
  • Stettner Josef
    General overview on bioprocess engineering with focus on USP (upstream processing), DSP (downstream processing) and sterile operations; among others but not exclusive:
    * Reactor types used in USP
    * Stirred tank bioreactor (STR): process parameter monitoring and control, engineering aspects and practical considerations, modes of operation, scale-up/-down of mixing & aeration, case studies & current trends
    * Basic DSP operations incl. technologies for cell removal, cell disruption and product purification
    * Different options and technical considerations to achieve and maintain sterility for aseptic operations
    A spotlight on biopharmaceutical processing as biologics (hormones, antibodies, fusion proteins, …) were becoming so important.